Patent · US Expired

Arylthiazolidinedione and aryloxazolidinedione derivatives

US6399640B1 · kind B1 · utility

2Cited by
17References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 16, 2000
Grant dateJun 4, 2002
Priority date
Expiry dateJun 16, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Substituted 5-aryl-2,4-thiazolidinediones or 5-aryl-2,4-oxazolidinediones that also carry a second substituent in the 5-position of the heterocyclic ring are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR &agr;, &dgr; and/or &ggr; mediated diseases, disorders and conditions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.