N-(3-benzofuranyl) urea-derivatives

US6399657B1 · kind B1 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gabriele Braunlich · Wuppertal, DE
• Rüdiger Fischer · Pulheim, DE
• Mazen Es-Sayed · Langenfeld, DE
• Rolf Henning · Wuppertal, DE
• Michael Sperzel · Wuppertal, DE
• Karl-Heinz Schlemmer · Wuppertal, DE
• Ulrich Nielsch · Wuppertal, DE
• Stephen Tudhope · Windsor, GB
• Graham Sturton · Maidenhead, GB
• Trevor S. Abram · Marlow, GB
• Mary F. Fitzgerald · Yarnton, GB

Key dates

• Filing date: May 21, 1999
• Grant date: Jun 4, 2002
• Expiry date: May 21, 2019

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D405/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

N-(3-benzofuranyl)urea-derivatives are prepared by reacting of 3-amino-substituted benzofuranes with appropriate substituted isocyanates or isothiocyanates. The N(3-benzofuranyl)urea-derivatives can be used as active ingredients in medicaments particularly for the treatment of acute and chronic inflammatory processes.