Trypanosoma cruzi antigen, gene encoding therefore, and methods of detecting and treating chagas disease
US6403103B1 · kind B1 · utility
3Cited by
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18Claims
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Key dates
| Filing date | Dec 10, 1997 |
| Grant date | Jun 11, 2002 |
| Priority date | — |
| Expiry date | Dec 10, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The nucleotide sequence of Tc100, a gene encoding a new antigenic protein from Trypanosoma cruzi called PTc100, is disclosed. The amino acid sequence of the PTc100 protein is also disclosed, along with the amino acid sequence of the dominant antigenic epitope of the PTc100 protein. The PTc100 protein and Tc100 gene, or a fragment thereof, modified or otherwise, can be used directly or indirectly for the detection of Trypanosoma cruzi, or for the monitoring of an infection generated by T. cruzi in man or animals.
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