Preparation of biodegradable, biocompatible microparticles containing a biologically active agent
US6403114B1 · kind B1 · utility
11Cited by
23References
15Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 3, 2001 |
| Grant date | Jun 11, 2002 |
| Priority date | — |
| Expiry date | Aug 3, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2985
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for preparing biodegradable, biocompatible microparticles. A first phase is prepared that includes a biodegradable, biocompatible polymer, an active agent, and a solvent. A second phase is prepared. The first and second phases are combined to form an emulsion in which the first phase is discontinuous and the second phase is continuous. The discontinuous first phase is separated from the continuous second phase. The residual level of solvent in the discontinuous first phase is reduced to less than about 2% by weight.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.