Diagnostic method using expression of MN/CA9 protein in ASCUS Pap smears
US6403327B1 · kind B1 · utility
0Cited by
10References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 16, 2000 |
| Grant date | Jun 11, 2002 |
| Priority date | — |
| Expiry date | May 16, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/3069
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Determining the presence of cancerous or pre-cancerous cervical lesions from ASCUS-diagnosed Pap smear cells by observing the distribution of MN/CA9 antigen expressed on atypical or normal cells and diagnosing (a) significant lesions when MN/CA9 antigen is observed on atypical cells, (b) low grade lesions when MN/CA9 antigen is absent from atypical cells but is present on normal endocervical cells, and (c) a benign condition when MN/CA9 antigen is absent from both atypical cells and normal endocervical cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.