Xanthone compounds, their preparation and use as medicament

US6403636B1 · kind B1 · utility

Assignee

• Zentaris GmbH · DE

Inventors

• Vichai Reutrakul · Bangkok, TH
• Thaiwatchai Santisuk · Bangkok, TH
• Gerhard Noessner · Offenbach, DE
• Juergen Schmidt · Goldkronach, DE
• Bernd Nickel · Mühltal, DE
• Thomas Klenner · Ingelheim am Rhein, DE
• Sebastian Hose · Würzburg, DE

Key dates

• Filing date: Jun 28, 2000
• Grant date: Jun 11, 2002
• Expiry date: Jun 28, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention relates to novel xanthone compounds, their preparation and use as medicament. More particularly this invention is directed to the isolation of the novel xanthone natural product sootepenseone from Dasymaschalon sootepense Craib, Annonaceae, its identification and derivatization, and the use of sootepenseone and its derivatives as anticancer agents.