Patent · US Expired

Salts of thrombin inhibitors

US6407067B1 · kind B1 · utility

9Cited by
2References
10Claims
0Family size

Assignee

Inventor

Key dates

Filing dateApr 27, 2000
Grant dateJun 18, 2002
Priority date
Expiry dateApr 27, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Compounds having thrombin inhibiting activity of the general formula I or II wheren is 0.5, 1, 2 andHX is  and HX is optionally substituted once or twice by methyl, ethyl or hydroxyl, and the tautomers and stereoisomers thereof, which compounds have greater thermal stability betaines, and salts of mineral acids or C1-C4-carboxylic acids.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.