Method for inhibiting cytokine production by cells

US6407081B1 · kind B1 · utility

Assignee

• Previsan AG · CH

Inventors

• Michel Goldman · Brussels, BE
• Helene Margery · Bierges, BE
• Patrick Adelin Oscar Robberecht · Brussels, BE
• Jean Pierre Robert Tassignon · Brussels, BE
• Michel Vandevelde · Ieper, BE

Key dates

• Filing date: Oct 13, 2000
• Grant date: Jun 18, 2002
• Expiry date: Oct 13, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns a method for inhibiting cytokine production by cells, in particular animal or human cells, and their secretion, which consists in applying on said cells at least an azo compound derivatives corresponding to formula (I), in which A represents a carboxyl or a group (a); B represents a carboxyl or a group (b); R1, R2, R3 and R4=H, Hal, OH or a hydrocarbon radical, R1 and R2 as well as R3 and R4 capable of being a heterocyclic ring; X1 and X2=O or NR5, where R5=H, Hal, a hydrocarbon radical or a nitro group.