N-triazolylmethyl-piperazine compounds with neurokinin-receptor antagonist activity

US6407106B1 · kind B1 · utility

Assignee

• Solvay Pharmaceuticals, GmbH · US

Inventors

• Daniel Jasserand · Paris, FR
• Uwe Schoen · Burgdorf, DE
• Holger Sann · Hannover, DE
• Reinhard Brueckner · Hannover, DE
• Christian Eeckhout · Winsen (Aller), DE

Key dates

• Filing date: Jul 27, 2001
• Grant date: Jun 18, 2002
• Expiry date: Jul 27, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/14
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

N-triazolylmethyl-piperazine compounds which exhibit neurokinin receptor antagonistic activity corresponding to the formula I: whereinR1, R2 and R3 have the meanings given in the specification; pharmaceutical compositions containing these compounds; a process for preparing these compounds, and intermediate products of this process.