Production of thrombin inhibitors
US6410272B1 · kind B1 · utility
7Cited by
4References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 27, 1990 |
| Grant date | Jun 25, 2002 |
| Priority date | — |
| Expiry date | Feb 27, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/33
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for the production and secretion of proteins with hirudin activity in an eukaryotic host organism is provided. There are also provided hybrid vectors comprising a DNA sequence encoding a signal peptide upstream of and in reading frame with the structural gene for desulphatohirudin, and eukaryotic host organisms transformed with said hybrid vectors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.