Patent · US Expired

Compounds and therapies for the prevention of vascular and non-vascular pathologies

US6410587B1 · kind B1 · utility

61Cited by
92References
35Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 5, 2000
Grant dateJun 25, 2002
Priority date
Expiry dateMay 5, 2020

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/323
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.