Cassette for facilitating optical sectioning of a retained tissue specimen
US6411434B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 17, 2000 |
| Grant date | Jun 25, 2002 |
| Priority date | — |
| Expiry date | Feb 17, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2001/315
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A cassette for retaining a specimen of surgically exposed tissue from a patient in an orientation that facilitates optical sectioning of the tissue by a confocal microscopic or other optical imaging microscope. The cassette includes a base member having a rigid optically transparent window upon which a tissue specimen is situated, a pliable membrane locatable over a substantial portion of the base member including the window, and an upper member, having an aperture therethrough, which can cover the base member to provide an enclosed cavity between the membrane and the window sealing the tissue specimen therein. With the tissue specimen in the enclosed cavity of the cassette, the edges of the tissue specimen may be positioned planar against the window and retained in that position by bonds formed between the membrane and window at multiple points or locations around the tissue specimen. The specimen retained in the cavity is viewable through the aperture of the upper member and imagible by a confocal microscope, or other optical imaging microscope, through the window of the base member. The base member has an injection port through which fluid may be inserted and removed from the ca…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.