Apparatus and method for preparative supercritical fluid chromatography

US6413428B1 · kind B1 · utility

Assignee

• Berger Instruments, Inc. · US

Inventors

• Terry A. Berger · Newark, US
• Kimber D. Fogelman · Hockessin, US
• L. Thompson Staats, III · McKeesport, US
• Mark Nickerson · Landenberg, US
• Paul F. Bente, III · New Garden Township, US

Key dates

• Filing date: Jun 26, 2000
• Grant date: Jul 2, 2002
• Expiry date: Sep 30, 2020

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N30/82
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

A fractionated sample collection process and device having at least one pressurized chamber used to gather and store liquid samples generated from a flow stream containing a mixture of highly compressed gas, compressible liquid, or supercritical fluid and a relatively incompressible liquid. A bank of multiple collection chambers is secured together in a frame to form a cassette unit. Each collection chamber may house a replaceable liner such as a test tube vial, to hold a fractionated liquid phase sample. After filling with sample, a collection chamber is returned to a clean state and ready for refilling with a new sample by manually or automatically replacing the liner.