Production of proteins by cell culture
US6413746B1 · kind B1 · utility
84Cited by
0References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Sep 11, 2000 |
| Grant date | Jul 2, 2002 |
| Priority date | — |
| Expiry date | Sep 11, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2500/36
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for obtaining a protein by culture of hybridoma cells, wherein said protein is an immunoglobulin, are disclosed. The methods involve culturing animal hybridoma cells in continuous presence of an alkanoic acid or salt thereof, which enhances protein production, wherein said alkanoic acid or salt thereof is present at 2 concentration range of 0.1 mM to 200 mM.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.