High throughput screening of gene function using adenoviral libraries for functional genomics applications
US6413776B1 · kind B1 · utility
8Cited by
16References
36Claims
0Family size
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Key dates
| Filing date | Jun 12, 1998 |
| Grant date | Jul 2, 2002 |
| Priority date | — |
| Expiry date | Jun 12, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/42
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel adenovirus vectors and methods for their use are provided to determine the function of the product(s) of one or more sample nucleic acids. The sample nucleic acids are synthetic oligonucleotides, DNA, or cDNA and encode polypeptides, antisense nucleic acids or GSEs. The sample nucleic acids are expressed in a host by recombinant adenovirus vectors to alter at least one phenotype of the host. The altered phenotype(s) is identified as a means to assign a biological function to the product(s) encoded by the sample nucleic acid(s).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.