Antimicrobial composition containing parachlorometaxylenol (PCMX)
US6413921B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 1, 2000 |
| Grant date | Jul 2, 2002 |
| Priority date | — |
| Expiry date | Aug 1, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2800/75
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an antimicrobial composition for disinfection of a skin surface in preparation for surgery. The antimicrobial composition comprises parachlorometaxylenol (PCMX) and an anionic surfactant composition which exhibits both a high degree of antimicrobial efficacy and low skin irritability properties. In a preferred embodiment, the composition comprises an anionic surfactant composition comprising a surfactant having a hydrophobic portion consisting of a linear alkyl and a hydrophilic portion having ethoxylation termination with a sulfonate anionic group, and a sarcosine surfactant. A preferred surfactant composition further comprises a foaming anionic surfactant, such as sodium lauryl sulfate. The antimicrobial composition can be used in skin disinfecting formulations, such as scrub formulations and pre-operative skin disinfecting formulations. In one embodiment, the composition comprises about 3.3% parachlorometaxylenol. The composition can be used as a surgical scrub formulation or in various pre-surgical skin disinfecting products, including sponges, swabs and topical application devices.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.