Purine derivatives having phosphodiesterase iv inhibition activity

US6413975B1 · kind B1 · utility

Assignee

• Euro-Celtique S.A. · LU

Inventors

• Mark Chasin · Manalapan, US
• David Cavalla · Cambridge, GB
• Peter Hofer · Liestal, CH
• Andre Gehrig · Basel, CH
• Peter Wintergerst · Basel, CH

Key dates

• Filing date: Mar 31, 2000
• Grant date: Jul 2, 2002
• Expiry date: Mar 31, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D473/34
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are compounds of the formula: whereinR3, R6a, R6b and R8 are substituted as disclosed herein. The compounds are effective in effecting PDE IV inhibition in patients in need thereof.