Cinnamamide derivatives and drug compositions containing the same
US6413995B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 21, 2001 |
| Grant date | Jul 2, 2002 |
| Priority date | — |
| Expiry date | May 21, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to cinnamamide derivatives having the following formula whereinR1 represents a hydroxyl group, a C1-6-alkoxy group, an arylalkoxy group or a substituted or unsubstituted amino group;R2 and R3 are same or different, each of which represents a hydrogen atom, a halogen atom or a C1-4-alkyl group;R4 represents a hydrogen atom or a C1-6-alkyl group;R5 represents a hydrogen atom, a C1-6-alkyl group or an aryl group;R6 represents a hydrogen atom, a C1-6-alkyl group, a cyano group or a C1-6-alkoxy-carbonyl group;W represents an oxygen atom, a sulfur atom, an imino group, a methylene group, a hydroxymethylene group or a carbonyl group;X and Y are same or different, each of which represents an oxygen atom or a sulfur atom;m represents an integer of 0 to 2;n represents an integer of 1 to 3; andwhen m is 0, a group: —C(R2)(R3)—W— may represent a vinylene group;or a pharmaceutically acceptable salt thereof; and a pharmaceutical composition containing the above compound, in particular, an immunomodulatory agent and a prophylactic or therapeutic agent for nephrotic syndrome, circulatory disorders or respiratory diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.