Radiopharmaceuticals for imaging infection and inflammation
US6416733B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 3, 1997 |
| Grant date | Jul 9, 2002 |
| Priority date | — |
| Expiry date | Oct 3, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F13/005
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides novel radiopharmaceuticals useful for the diagnosis of infection and inflammation, reagents and kits useful for preparing the radiopharmaceuticals, methods of imaging sites of infection and/or inflammation in a patient, and methods of diagnosing diseases associated with infection or inflammation in patients in need of such diagnosis. The radiopharmaceuticals bind in vivo to the leukotriene B4 (LTB4) receptor on the surface of leukocytes which accumulate at the site of infection and inflammation. The reagents provided by this invention are also useful for the treatment of diseases associated with infection and inflammation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.