Dental composition for treating hypersensitive teeth
US6416745B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 3, 2001 |
| Grant date | Jul 9, 2002 |
| Priority date | — |
| Expiry date | May 3, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/127
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides dental compositions and methods for treating dentinal hypersensitivity teeth based on the discovery that anionic liposomes possess the capacity to induce mineral formation in the dentinal tubules which partially or fully block them. The subject compositions comprise the liposomes and a suitable carrier and are advantageous in that they can deliver additional agents useful in the treatment of dentinal hypersensitivity, particularly nerve desensitizing agents, to the tubules. The liposomes of the invention are further advantageous in that they are stable to conventional sources of fluoride ion conventionally used as anti-caries agents. The methods of the present invention utilize the subject composition to effect blocking of the dentinal tubules and to simultaneously deliver other treatment agents such as nerve desensitizing agents for the combined benefits thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.