Quinolines and quinazolines useful in therapy
US6417194B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 7, 2000 |
| Grant date | Jul 9, 2002 |
| Priority date | — |
| Expiry date | Feb 7, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula I, whereinR1 represents C1-4 alkoxy optionally substituted by one or more fluorine atoms;R2 and R3 independently represent H or C1-6 alkoxy (which is optionally substituted);R4 represents a 4-, 5-, 6- or 7-membered heterocyclic ring, the ring being optionally fused to a benzene ring or a 5- or 6-membered heterocyclic, the ring system as a whole being optionally substituted;X represents CH or N; andL is absent,or represents a cyclic group of formula Ia, or represents a chain of formula Ib, and pharmaceutically acceptable salts thereof; are useful in therapy, in particular in the treatment of benign prostatic hyperplasia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.