Levobupivacaine as an analgesic agent

US6417201B1 · kind B1 · utility

Assignee

• Darwin Discovery Limited · GB

Inventors

• Hazel Judith Bardsley · Cambridge, GB
• Robert William Gristwood · Cambridge, GB
• Andrew John McGlashan Richards · Cambridge, GB

Key dates

• Filing date: Jul 12, 2000
• Grant date: Jul 9, 2002
• Expiry date: Jul 12, 2020

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K31/445
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Levobupivacaine ((S)-1-butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide) is useful as an anesthetic, particularly in a patient who is disposed to adverse systemic side-effects, e.g., one who is CNS-compromised or predisposed to CNS side-effects. A unit dose of levobupivacaine comprising at least 75 mg to less than 200 mg of levobupivacaine is described herein.