Methods of screening for agents that inhibit aggregation of polypeptides
US6420122B1 · kind B1 · utility
10Cited by
1References
34Claims
0Family size
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Key dates
| Filing date | Sep 27, 1999 |
| Grant date | Jul 16, 2002 |
| Priority date | — |
| Expiry date | Sep 27, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6896
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods of identifying compounds that disrupt aggregation of aggregation-disposed polypeptides, such as huntingtin or beta-amyloid protein, are disclosed. Furthermore, an artificial polypeptide that contains an extended polyglutamine region and DNA that encodes the polypeptide are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.