Production of multimeric protein by cell fusion method
US6420140B1 · kind B1 · utility
44Cited by
7References
27Claims
0Family size
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Key dates
| Filing date | Jan 24, 2001 |
| Grant date | Jul 16, 2002 |
| Priority date | — |
| Expiry date | Jan 24, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention features a method of producing a multimeric protein from a hybrid cell formed from the fusion of two or more cells, each of which cell is engineered to express one component of the multimeric protein, as well as a method for screening for successful fusion of the cells to produce a desired hybrid cell. The methods of the invention are widely applicable to the production of proteins having two or more components.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.