Recombinant adenoviruses containing an inducible promoter controlling a gene of viral origin
US6420170B1 · kind B1 · utility
6Cited by
5References
32Claims
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Assignee
Inventors
Key dates
| Filing date | Dec 19, 1997 |
| Grant date | Jul 16, 2002 |
| Priority date | — |
| Expiry date | Dec 19, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/15
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A recombinant adenovirus in which the expression of a nucleic acid sequence coding for at least one homologous or heterologous gene of viral origin is placed under the control of an inducible promoter, is disclosed. The use of such recombinant adenoviruses for preparing AAVs, and a complementary cell line and preparation method therefor, are also disclosed. Furthermore, pharmaceutical compositions containing such an adenovirus are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.