Use of 7 &agr;-substituted steroid to treat neuropsychiatric, immune or endocrine disorders
US6420353B1 · kind B1 · utility
6Cited by
4References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 8, 1998 |
| Grant date | Jul 16, 2002 |
| Priority date | — |
| Expiry date | Oct 8, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Use is provided for a 7&agr;-hydroxy or 7-oxo substituted 3&bgr;-hydroxy-steroid possessing the carbon skeleton of cholesterol, androsterone, pregnenolone or estradiol, or an analogue thereof substituted independently at one or both of the 7- and 3-positions with an ester or ether group, in the manufacture of a pharmaceutical composition for the therapy of neuropsychiatric, immune and/or endocrine disorders or for inducing cognitive enhancement. Uses for Cyp7b enzymes in producing such steroids is also provided together with various novel steroids and test kits and methods for diagnosing the disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.