Proton pump inhibitors
US6420384B2 · kind B2 · utility
26Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 18, 2000 |
| Grant date | Jul 16, 2002 |
| Priority date | — |
| Expiry date | Dec 18, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65616
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds and methods of treating or preventing bone disorders including osteoporosis, rheumatoid arthritis, and metastatic bone disease are provided. The inventive compounds comprise a bone targeting moiety and a payload. The payload portion of these inventive compounds inhibit the proton pump of osteoclasts, thereby, reducing bone resorption. Compounds of the present invention include compounds of the following formula:
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.