Constrast media

US6423296B1 · kind B1 · utility

Assignee

• Amersham Health AS · NO

Inventors

• Wolfgang H. H. Gunther · Hersbruck, DE
• Kenneth Kellar · Wayne, US
• Dennis Fujii · Downingtown, US
• Vinay C. Desai · Phoenixville, US
• Christopher Black · Norristown, US
• Marshall Beeber · Royersford, US
• Jennifer Wellons · Wayne, US
• Anne Kjersti Fahlvik · Oslo, NO
• Jasbir Singh · Gilbertsville, US
• Edward R. Bacon · East Greenbush, US
• Gregory L. McIntire · West Chester, US
• Robert Alan Snow · Wayne, US
• Brian Weekley · Wayne, US
• Torgrim Engell · Oslo, NO
• Michel Gacek · Tvedestrand, NO
• David L. Ladd · Whitehall, US
• Anne Naevestad · Oslo, NO
• George Na · Wayne, US
• Barbara Yuan · Villanova, US
• Jack Stevens · Wayne, US

Key dates

• Filing date: Feb 22, 1999
• Grant date: Jul 23, 2002
• Expiry date: Feb 22, 2019

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B82Y5/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to MR contrast media containing composite nanoparticles, preferably comprising a superparamagnetic iron oxide core provided with a coating comprising an oxidatively cleaved starch coating optionally together with a functionalized polyalkyleneoxide which serves to prolong blood residence.