Inhibiting oxidative degradation of pharmaceutical formulations
US6423351B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 9, 2001 |
| Grant date | Jul 23, 2002 |
| Priority date | — |
| Expiry date | Mar 9, 2021 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S424/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods for inhibiting oxidative degradation of pharmaceutical formulations comprising at least one oxidation-susceptible active drug ingredient which methods comprise adding an oxidation-inhibiting amount of a ferrous ion source, preferably in the form of a pharmaceuticalexcipient, to the formulation.The invention further provides pharmaceutical formulations comprising at least one oxidation-susceptible active drug ingredient and an oxidation-inhibiting amount of a ferrous iron source, preferably in the form of a pharmaceuticalexcipient.The invention still further provides for the use of a ferrous ion source as an anti-oxidant in pharmaceutical formulations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.