Polynucleotide sequences of human EDG-1c
US6423508B1 · kind B1 · utility
3Cited by
3References
8Claims
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Key dates
| Filing date | Mar 4, 1999 |
| Grant date | Jul 23, 2002 |
| Priority date | — |
| Expiry date | Mar 4, 2019 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC40B40/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Human EDG-1c polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Human EDG-1c is identified as a selective receptor for sphingosine-1-phosphate (“S-1-P”) and for di-hydro S-1-P. Also diclsosed are methods for discovering agonists and antagonists of the interaction between S-1-P and di-hydro S-1-P and their cellular receptor, human EDG-1c, which may have utility in the treatment of several human diseases and disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.