Patent · US Expired

Microorganism lactamase enzyme obtained therefrom and their use

US6423522B1 · kind B1 · utility

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8Claims
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Assignee

Inventors

Key dates

Filing dateFeb 22, 2000
Grant dateJul 23, 2002
Priority date
Expiry dateFeb 22, 2020

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P41/006
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A lactamase enzyme having good stability, capable of hydrolysing an enantiomer of the bicyclic lactam, 2-azabicyclo[2.2.1]hept-5-en-3-one, to give (−) lactam and (+) amino acid, has been found in a strain of Comamonas acidivorans. The enzyme has been isolated and cloned, and its structure identified.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.