Matrix-free osteogenic devices, implants and methods of use thereof
US6426332B1 · kind B1 · utility
66Cited by
8References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 22, 2001 |
| Grant date | Jul 30, 2002 |
| Priority date | — |
| Expiry date | Jun 22, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2430/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods for inducing bone formation in a mammal sufficient to fill a defect defining a void, wherein osteogenic protein is provided alone or dispersed in a biocompatible non-rigid, amorphous carrier having no defined surfaces. The methods and devices provide injectable formulations for filling critical size defects, as well as for accelerating the rate and enhancing the quality of bone formation in non-critical size defects.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.