Heterocyclic carboxamide-containing thiourea inhibitors of herpes viruses containing phenylenediamine group

US6426355B1 · kind B1 · utility

Assignee

• Amerimas Home Products, Inc. · US

Inventors

• Jonathan Bloom · Hartsdale, US
• Kevin Joseph Curran · Nyack, US
• Martin DiGrandi · Piermont, US
• Russell Dushin · Old Lyme, US
• Thomas H. Jones · Naperville, US
• Stanley Lang · Carlsbad, US
• Adma Ross · Suffern, US
• Eugene A. Terefenko · Quakertown, US
• Bryan O'Hara · Norwood, US

Key dates

• Filing date: Sep 27, 2000
• Grant date: Jul 30, 2002
• Expiry date: Sep 27, 2020

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds having the formula: wherein R1-R5, X and G are described herein and which are useful in the treatment of diseases associated with herpes viruses including human cytomegalovirus, herpes simplex viruses, Epstein-Barr virus, varicella-zoster virus, human herpesviruses-6 and -7, and Kaposi herpesvirus.