Patent · US Expired

Formulations of tocopherols and methods of making and using them

US6426362B1 · kind B1 · utility

100Cited by
24References
22Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 6, 2000
Grant dateJul 30, 2002
Priority date
Expiry dateOct 6, 2020

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K45/06
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Non-naturally-occuring compositions for use in amelioration of disruption of energy metabolism secondary to stress are described. The compositions comprise a tocopherol and/or a derivative thereof, and a synergist, and are particularly suited for use as nutritional supplements. Synergists include, but are not limited to, flavonoids and lactoferrin and/or derivatives thereof. Compositions comprising an optimized formulation comprising a tocopherol and an additional compound such as daidzein or biochanin A are also described. Methods of making these compositions and methods of ameliorating injury(ies) or disruption of energy metabolism secondary to stress, comprising administering such compositions, are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.