Covalently linked oligonucleotide minor groove binder conjugates
US6426408B1 · kind B1 · utility
10Cited by
6References
7Claims
0Family size
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Key dates
| Filing date | Feb 18, 2000 |
| Grant date | Jul 30, 2002 |
| Priority date | — |
| Expiry date | Feb 18, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6813
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Minor groove binding molecules are covalently bound to oligonucleotides which in their base sequence are complementary to a target sequence of single stranded or double stranded DNA, RNA or hybrids thereof. The covalently bound oligonucleotide minor groove binder conjugates strogly bind to the target sequence of the complementary strand.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.