Compositions and methods for specifically targeting tumors
US6428788B1 · kind B1 · utility
47Cited by
2References
53Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 30, 1996 |
| Grant date | Aug 6, 2002 |
| Priority date | — |
| Expiry date | Aug 30, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method and compositions for specifically delivering an effector molecule to a tumor cell. The method involves providing a chimeric molecule comprising an effector molecule attached to a targeting molecule that specifically binds an IL-13 receptor and contacting a tumor cell with the chimeric molecule in the presence of an interleukin-4 receptor (IL-4R) blocker.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.