Method and means for producing high titer, safe, recombinant lentivirus vectors
US6428953B1 · kind B1 · utility
58Cited by
2References
9Claims
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Key dates
| Filing date | Jun 26, 2000 |
| Grant date | Aug 6, 2002 |
| Priority date | — |
| Expiry date | Jun 26, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Lentiviral vectors modified at the 5′ LTR or both the 5′ and 3′ LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.