Immunostimulatory nucleic acid molecules for activating dendritic cells
US6429199B1 · kind B1 · utility
261Cited by
12References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1998 |
| Grant date | Aug 6, 2002 |
| Priority date | — |
| Expiry date | Nov 13, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/056
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates generally to methods and products for activating dendritic cells. In particular, the invention relates to oligonucleotides which have a specific sequence including at least one unmethylated CpG dinucleotide which are useful for activating dendritic cells. The methods are useful for in vitro, ex-vivo, and in vivo methods such as cancer immunotherapeutics, treatment of infectious disease and treatment of allergic disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.