Treatment of chronic hypertension and related conditions with thiol complexes
US6429219B1 · kind B1 · utility
7Cited by
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4Claims
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Key dates
| Filing date | May 3, 2000 |
| Grant date | Aug 6, 2002 |
| Priority date | — |
| Expiry date | May 3, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/555
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to the synthesis of certain complexes of cysteine, N-acetylcysteine, N-(2-mercaptopropionyl)glycine, and L-2-oxothiazolidine-4-carboxylate and to the nutritional use of these and other related individual or complexed thiol-contributing glutathione predecessors. Clinical uses for these molecules and complexes in the beneficial modification of various physiological conditions and functions associated with aging, chronic glaucoma, diabetes mellitus, insulin resistance, macular degeneration, neurodegenerative diseases and vasoconstriction are described in particular.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.