Monitoring constituents of an animal organ using statistical correlation
US6430513B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 7, 2000 |
| Grant date | Aug 6, 2002 |
| Priority date | — |
| Expiry date | Jan 7, 2020 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/49
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Constituents such as oxy- and deoxy-hemoglobin are monitored non-invasively in an animal organ such as a brain with a spectrometric instrument by passing radiation through the organ. Concentrations are computed from the spectral intensities and from a statistical correlation model. To predetermine the correlation model, the procedures are effected for a plurality of organs of a same type with each organ having established concentrations of the selected constituents, and the correlation model is statistically determined from the concentrations and corresponding intensities. For more accuracy computations are normalized to path length which may be determined by utilizing several discrete wavelengths with RF modulations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.