Treatment of and/or prophylaxis against brain and spinal cord injury

US6432434B1 · kind B1 · utility

Assignee

• The United States of America as represented by the Secretary of the Army · US

Inventors

• James L. Meyerhoff · Silver Spring, US
• Joseph Long · Clarksville, US
• Michael Koenig · Dormagen, DE

Key dates

• Filing date: Apr 21, 2000
• Grant date: Aug 13, 2002
• Expiry date: Apr 21, 2020

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B82Y5/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The administration of &agr;-lipoic acid (&agr;LA) and dihydrolipoic acid (DHL) both as a preventive measure before exposure to conditions which may cause damage, such as rapid changes in atmospheric pressure, and as a means of preventing or ameliorating damage arising from such injury provides benefits not currently available. The active agents may be administered systemically or to the injured tissue. For example, when there is spinal cord injury, the active agents may be administered intrathecally.