Methods of screening modulators of opioid receptor activity
US6432652B1 · kind B1 · utility
2Cited by
0References
3Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 14, 1995 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | Mar 14, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/705
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Genes encoding opioid receptors (including opioid-like receptor (ORL) proteins) can be retrieved from vertebrate libraries using the murine probe disclosed herein under low-stringency conditions. The DNA sequence shown in FIG. 5 or its complement can be used to obtain the human delta, kappa and mu genes as well as the murine mu gene and human ORL-1. The probe provided encodes the murine delta opioid receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.