Polynucleotides encoding staphylcoccal FAB I enoyl-ACP reductase
US6432670B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1999 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | Apr 15, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Prokayrotic FAB I polypeptides and DNA (RNA) encoding such FAB I and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such FAB I for the treatment of infection, such as bacterial infections. Antagonists against such FAB I and their use as a therapeutic to treat infections, such asstaphylococcal infections are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to the presence of FAB I nucleic acid sequences and the polypeptides in a host. Also disclosed are diagnostic assays for detecting polynucleotides encoding FAB I and for detecting the polypeptide in a host.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.