Patent · US Expired

Substances KF-1040 and process for producing of the same

US6432682B1 · kind B1 · utility

4Cited by
1References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 8, 2000
Grant dateAug 13, 2002
Priority date
Expiry dateAug 8, 2020

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/822
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A process for producing a substance KF-1040A represented by formula (I), and another substance KF-1040B represented by formula (II), which comprises culturing microorganisms capable of producing the substances KF-1040A and KF-1040B, thus accumulating these KF-1040A and/or KF-1040B in the liquid culture and harvesting the same from the culture. Because of the activities of inhibiting diacyloglycerol transferase and sphingomyelinase, the above substances are useful in preventing and treating arteriosclerosis, obesity, thrombus, inflammation and immune function-related diseases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.