Human desaturase gene and uses thereof
US6432684B1 · kind B1 · utility
72Cited by
2References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 8, 1999 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | Jan 8, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention relates to the identification of a gene involved in the desaturation of polyunsaturated fatty acids at carbon 5 (i.e., “human &Dgr;5-desaturase”) and to uses thereof. In particular, human &Dgr;5-desaturase may be utilized, for example, in the conversion of dihomo-&ggr;-linolenic acid (DGLA) to arachidonic acid (AA) and in the conversion of 20:4n-3 to eicosapentaenoic acid (EPA). AA or polyunsaturated fatty acids produced therefrom may be added to pharmaceutical compositions, nutritional compositions, animal feeds, as well as other products such as cosmetics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.