Patent · US Expired

Method for the production of 1,3-propanediol by recombinant organisms comprising genes for vitamin B12 transport

US6432686B1 · kind B1 · utility

55Cited by

4References

13Claims

0Family size

Assignees

E.I. DU PONT DE NEMOURS AND COMPANY · US
GENENCOR INTERNATIONAL, INC. · US

Inventors

Ben A. Bulthuis · Leiden, NL
Gregory M. Whited · Belmont, US
Donald E. Trimbur · Palo Alto, US
Anthony A. Gatenby · Wilmington, US

Key dates

Filing date	May 10, 1999
Grant date	Aug 13, 2002
Priority date	—
Expiry date	May 10, 2019

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12P7/18
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Recombinant organisms are provided comprising genes encoding genes encoding glycerol dehydratase, 1,3-propanediol oxidoreductase, a gene encoding vitamin B12 receptor precursor(BtuB), a gene encoding vitamin B12 transport system permease protein(BtuC) and a gene encoding vitamin B12 transport ATP-binding protein (BtuD). The recombinant microorganism is contacted with a carbon substrate and 1,3-propanediol is isolated from the growth media.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.