Sensitive bioassay for detecting agonists of the aryl hydrocarbon receptor
US6432692B1 · kind B1 · utility
12Cited by
1References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 21, 1999 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | Jun 21, 2019 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2430/50
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Improved cellular assay systems for detecting polycyclic aromatic hydrocarbons, dioxins, PCBs, and other substances which are agonists of the aryl hydrocarbon receptor (AHR) are disclosed. The assays utilize one or more additional cellular proteins involved in the AHR signaling pathway, which improve the sensitivity and maximal responsiveness of the assay systems.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.