Inhibitors of urokinase and blood vessel formation
US6432922B1 · kind B1 · utility
9Cited by
5References
77Claims
0Family size
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Key dates
| Filing date | Jul 22, 1999 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | Jul 22, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel compounds having activity inhibitors of urokinase and in reducing or inhibiting blood vessel formation are provided. These compounds have an arginine or arginine mimic aldehyde or an arginine ketoamide group at P1. These compounds are useful in vitro for monitoring plasminogen activator levels and in vivo in treatment of conditions which are ameliorated by inhibition of or decreased activity of urokinase and in treating pathologic conditions wherein blood vessel formation is related to a pathologic condition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.