SF2809-I,II,III,IV,V and VI substances exhibiting chymase-inhibiting activities
US6432978B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | May 31, 2001 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | May 31, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
As novel compounds which possess a chymase-inhibiting activity and are useful as medicines for a variety of applications, there are provided SF2809-I substance, SF2809-II substance, SF2809-III substance, SF2809-IV substance, SF2809-V substance and SF2809-VI substance which are represented by the following general formula (VII) wherein R1 is a hydrogen atom, phenyl group or p-hydroxyphenyl group, and R2 is acetylamino group —NHCOCH3 or hydroxyl group, or pharmaceutically acceptable salts thereof, and which possess the chymase-inhibiting activity. Also provided is a process for the preparation of the above SF2809 substances, as well as a pharmaceutical composition comprising one of those substances.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.