Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US6433155B1 · kind B1 · utility
86Cited by
7References
23Claims
0Family size
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Key dates
| Filing date | Sep 24, 1997 |
| Grant date | Aug 13, 2002 |
| Priority date | — |
| Expiry date | Sep 24, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An isolated polynucleotide at least 60% homologous to SEQ ID NO: 1, 3, 5 or 18 encoding a SARP polypeptide; vectors comprising a polynucleotide sequence encoding at least 11 consecutive amino acids of &agr;SARP polypeptide; a host cell transformed with an isolated polynucleotide or vector; antibodies specific for SARP and use of such polynucleotides and antibodies in diagnostic and therapeutic method. Therapeutic uses of antibodies and polynucleotides of sarp. Methods for treating diseases related to the regulation of SARP expression in tissue and bodily fluid samples, including cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.